Synthesis of 11-cis-retinol and Its Incorporation into FeO Nano Particles

  • Sheng Lin
  • Jon Rainier

Abstract

The light sensitivity of 11-cis-retinoid makes it an ideal chromophore. Since retinoids are not synthesized in human, eyes have evolved a unique recycling mechanism for generating 11-cis-retinal at retinal pigmented epithelium (RPE). The goals of my research are to synthesize 11-cis-retinol, attach it to phosphoric acid derivatives, and bind this complex to FeO Nanoparticles directly in order to deliver 11-cis-retinol as a therapeutic for eye diseases like macular degeneration and Leber's Congenital Amaurosis (LCA).
Published
2017-06-08
How to Cite
LIN, Sheng; RAINIER, Jon. Synthesis of 11-cis-retinol and Its Incorporation into FeO Nano Particles. Undergraduate Research Journal, [S.l.], june 2017. Available at: <http://epubs.utah.edu/index.php/URJ/article/view/3657>. Date accessed: 24 aug. 2017.
Issue
Section
College of Science